Developing partial-volume multi-beam FLASH with Proton Beams

Abstract:
The work for this doctoral research has been mainly developed at the German Cancer Research Center (DKFZ), Heidelberg, Germany, and at the Centro de Protonterapia Quirón salud (CPT), Madrid, Spain, with support from the Laboratório de Instrumentação e Física Experimental de Partículas (LIP), Lisbon, Portugal.

The main purpose of this work is to investigate how to implement multi-beam FLASH technique in proton radiotherapy, going from simulations using the treatment planning tool-kit MATRAD, to a clinical application with Raystation (RaySearch Laboratories, Stockholm, Sweden), a commercial treatment planning system (TPS), and delivery in with a ProteusOne protontherapy system (Ion Beam Applications, Leuven, Belgium).